Publishing genetic medicine research on the TGMI Gateway

The foundations of genetic medicine come from the published results of scientific and clinical research. Unfortunately, there are many barriers to publishing and accessing this vital information. To help remove these barriers we have set-up the TGMI Gateway, a new platform for publishing genetic medicine research.


The TGMI Gateway

The TGMI Gateway offers rapid, simple, citable, accessible publication of research outputs relevant to the mission of the TGMI to make genetic medicine work. Some of these are by the TGMI team, you may have read about them on the blog before. They include articles about DECoN, the ICR96 exon CNV validation series, the Quality Sequencing Minimum (QSM) and CoverView.

The other articles are part of the Genetic Medicine Research gateway area. This area is for articles by people outside the core TGMI, who are working on genetic medicine. You can find out more about the submission process and criteria on our gateway information page.


Why is the TGMI Gateway needed?

The TGMI Gateway offers rapid, simple, citable, accessible publication of genetic medicine research.

To deliver genetic medicine we need free, easy access to any relevant research information. The traditional systems for publishing research often restrict access to this vital information. They also do not incentivise publication of all the types of information we require. Scientific journals tend to prize novelty over utility. This deters researchers from doing many of the studies we urgently need, such as detailed, long-term clinical studies.

The traditional publication systems also take a very long time and are very expensive. It typically takes many months for a research paper to be published. The journals not only charge high fees to publish your research, many charge additional exorbitant fees if you want to make your work available to everyone. This means that many useful publications are behind paywalls requiring readers to pay around $30 for a 3000 word document.

So what are the benefits of publishing on the TGMI Gateway?


Publication on the TGMI gateway is rapid

All articles are published rapidly, as soon as they are accepted, after passing quality checks by Wellcome Open Research. The median time to publication is 8 days. Peer review by invited experts, suggested by the authors, takes place openly after publication. As soon as an article passes peer review it is indexed in PubMed and other databases, just like papers in traditional journals.


Publications on the TGMI gateway are open access

All articles and peer reviews are immediately open access and citable with their own DOI (digital object identifier). The expert peer reviews are also open access and citable with their own DOI. It is very useful and interesting to see the reviewers comments. Traditional journals do not make these available.


Publication on the TGMI gateway is free

Wellcome will cover the publication costs of any article published on the TGMI Genetic Medicine Research Gateway.


Publication on the TGMI gateway is based on utility

The TGMI Gateway wishes to support publication of any outputs useful to genetic medicine. We are keen for the gateway to include case reports, clinical practice articles, methods, protocols, software tools, data notes, as well as standard research articles. We also want to support publication of confirmatory results, negative findings and reanalyses of previous studies leading to new results. Work has to be original and the underlying data has to be made available. But no value judgements about the work are made.


A new way of publishing

This gateway is part of the Wellcome Open Research publishing platform. Wellcome Open Research allows Wellcome-funded researchers to publish any research outputs they think are useful. This includes methods, software, negative results, replications or refutation studies.

This publication model is different from traditional publication. Articles are published within days, and peer review takes place openly after publication. When an article passes peer review, it’s indexed in PubMed and other bibliographic databases. But even before this the paper is available to read and cite. And the peer reviews are also available to read and cite. This allows for a rapid and transparent exchange of information and ideas.

Wellcome isn’t the only organisation to have such a platform. The Bill & Melinda Gates Foundation has one too, as does the Health Research Board, and several others. All these open research publishing platforms are run on technology developed by F1000, who have been using it for their own publishing platform F1000Research since 2012.


Submit your genetic medicine research articles

Although Wellcome Open Research requires that authors are funded by Wellcome, the TGMI Gateway extends this to anyone working on research relevant to genetic medicine, regardless of funding source, as long as the article also fulfils the article guidelines for Wellcome Open Research.

Please have a look at our gateway information page and the Wellcome Open Research FAQs to familiarise yourself with some of the aspects of the system, such as the post-publication peer review process, article versioning, and the requirements to submit underlying data and suggest suitable reviewers.

You can use our enquiry form to get in touch with the TGMI if you have a manuscript that you’d like to submit. We look forward to hearing from you and welcome your submissions to our gateway.