Every Friday we post a blog on a topic related to genetic medicine. You can find our new posts on Twitter under the hashtag
#TGMIFriday. You can also sign up to get our blog posts direct to your email inbox. Please contact us if you have any suggestions for topics we should address.
The importance of genetic testing lies in its potential to provide health care professionals with an understanding of the genetic basis of why an individual’s signs and symptoms occur, which may inform preventive actions or treatment.
A genetic test aims to identify DNA variants. How good are genetic tests at this? How good are we at evaluating it?
Genetic testing is increasing, but who is having testing? And why?
Today the BRCA2 gene tells us a bit about herself, in our new interviews with genes series
Just a few decades ago, the concept of investigating someone’s genes to determine whether they were predisposed to a particular disease was still unheard of. This post describes the development of the very first DNA-based genetic test for a hereditary disease, the Huntington’s Disease test.
Gene editing has huge potential in the diagnosis and treatment genetic disease.
By publishing genetic medicine research on the TGMI Gateway on Wellcome Open Research, research results can be shared rapidly and openly.
Massive Attacks' Mezzanine album will be the first to be stored on DNA. Find out why DNA is the perfect data storage solution?
In this interview, James Ware shares why he's excited about the increasing amounts of available genetic data, and the strengths of the TGMI as a collaboration between different fields.
Read about the 9 Vs that will allow genetic medicine to harness the potential of big data.
The Gene Curation Coalition (GenCC) brings seven initiatives together to tackle key needs in the curation of links between genes and disease.
Today we introduce the Quality Sequence Minimum, (QSM) a simple, convenient shorthand for communicating the quality of a genetic test
A roundup of some of the recent TGMIFriday posts about phenotyping.
In this interview, TGMI team member Dominic McMullan shares his vision of connecting all diagnostic grade genetics data in a global resource.
Direct-to-consumer genetic testing is now a reality. Should we be worried? And if so, what about?
Sharing data is essential for genetic medicine to be successful. But how do we, could we and should we make data accessible?
Rare Disease Day represents not just one single group of diseases, but a large number of vastly different conditions, that each affect a small number of people. All of them are part of the rare disease community, but their individual needs are diverse.
TGMI team member David FitzPatrick talks about the importance of robust evidence for gene-disease associations, and the need for systematic phenotype descriptions.
We need to harness technology, global connectivity and patient-power to deliver a massive expansion in phenotyping.
In casual language, people often talk about "having the gene for a disease". This isn't correct - we all have those genes - so why does this expression exist, and how do we avoid it?